Natural Biomaterials as Instructive Engineered Microenvironments That Direct Cellular Function in Peripheral Nerve Tissue Engineering
نویسندگان
چکیده
منابع مشابه
Tissue-engineered Peripheral Nerve
Nerve injuries occur by a variety of mechanisms, including traumatic wounds, thermal or chemical damage, myelin or axonal degeneration, and acute compression. These injuries typically result in the loss of motor function, sensory function, or both. Functional recovery is regained upon complete axonal regeneration, which includes remyelination and reinnervation (i.e., synapse formation) of the a...
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Neural stem cells (NSCs) have been isolated from various speciesssuch as mice, rats, and humanssand from numerous regions in the developing and adult nervous systemsincluding the subventricular zone (SVZ), the subgranular zone of the hippocampus, the cortical neuroepithelium, and the spinal cord. In vivo, the NSC is encompassed by a microenvironment or niche that presents it with a repertoire o...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2021
ISSN: 2296-4185
DOI: 10.3389/fbioe.2021.674473